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A majority of dialysis patients begin therapy with low serum albumin levels (<4g/dL).2ÌýLow serum albumin is associated with a high risk of adverse health outcomes.3ÌýChoose a dialyzer with an albumin-sparing design.6

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Low serum albumin can increase your patients' risk of hospitalization4

Dialyzers that leak albumin may present a problem for patients4

Serum albumin is a beneficial protein and a key indicator of patient health. Once serum albumin levels drop below recommended levels, restoring normal levels is challenging.5ÌýDialyzers that have the potential to leak albumin during the course of treatmentÌýmay contribute to hypoalbuminemia.4

OptifluxÌýhigh-flux dialyzers have been shown to clear out harmful toxins while preserving serum albumin.6ÌýAfter six months of treatment with Optiflux, 87% of patients with hypoalbuminemia observed a mean increase in serum albumin levels.7

Optiflux dialyzers are prescribed by nephrologists more than 600 million times and counting.8

Learn more about how Optiflux®Ìýhigh-flux dialyzers can help your patients
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  1. NKF KDOQI Clinical Practice Guidelines. Am J Kidney Dis. 2000. Jun; 35(6 Suppl2}: S1-S140.
  2. United States Renal Data System.Ìý2022ÌýUSRDS Annual Data Report: Epidemiology of kidney disease in the United States.ÌýNational Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD,Ìý2022.
  3. Don BR, Kaysen G. 2004. Serum Albumin: Relationship to Inflammation and Nutrition. Seminars in Dialysis 17(6):432-7.
  4. Tsuchida, Kenji et al. Albumin Loss Under the Use of the High-Performance Membrane, Department of Kidney Disease (Artificial Kidney and Kidney Transplantation), Kawashima Hospital, Tokushima City, Tokushima, Japan.
  5. Kayson GA. Serum albumin concentration in dialysis patients: why does it remain resistant to therapy? Kidney Int. 2003;64 (Suppl 87):592-598.
  6. Ä¢¹½´«Ã½Ìý(2016). Instructions for Use: Optiflux High Flux EbeamÌýF50002272 Rev 07/2023
  7. Zhou, M., et al. Evaluation of Biomarkers in Chronic Hemodialysis Patients Dialyzed with Optiflux High-Flux Dialyzers, Poster Presentation, NKF Spring Clinical Meetings, 2020. Cause and effect not determined based on design.
  8. FMCNA data on file as of March 2023.
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Indications for use:ÌýOptiflux dialyzers are intended for patients with acute or chronic renal failure when conservative therapy is judged to be inadequate.

Caution:ÌýFederal (US) law restricts these devices to sale by or on order of a physician.

Note:ÌýRead the Instructions for Use for safe and proper use of these devices. For a complete description of hazards, contraindications, side effects, and precautions, see full package labeling atÌý. In rare cases, thrombocytopenia or hypersensitivity reactions including anaphylactic or anaphylactoid reactions to the dialyzer or other elements in the extracorporeal circuit may occur during hemodialysis. The suitability of a dialyzer for a particular treatment is the responsibility of the physician.

© 2024 Ä¢¹½´«Ã½. All Rights Reserved. Ä¢¹½´«Ã½, the triangle logo, and Optiflux are trademarks of Ä¢¹½´«Ã½ Holdings, Inc. or its affiliated companies. All other trademarks are the property of their respective owners. P/N 104341-01ÌýRev C 03/2024

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