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Antibodies or autoantibodies often play a key role in solid organ transplantation and in autoimmune disorders. This is frequently associated with the activation or agonistic stimulation of cell-surface mechanisms (e.g. complement factors) or with antagonistic blockage of certain receptors. Immunoadsorption therapy removes antibodies or immune complexes from the blood plasma. Due to its selectivity, it can treat a wide range of autoantibody mediated clinical indications.¹

During immunoadsorption, the targeted antibody classes are largely removed through strong binding affinity to different ligands of the adsorber matrix. This can alleviate the symptoms of disease, including in the acute state, and possibly prevent the diseaseÄ¢¹½´«Ã½™s progression.