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Disposables and fluids

Concerted range of products

Concerted range of products

Ä¢¹½´«Ã½ offers a wide range of individual disposables, pre-assembled kits and further products for CKRT - and in particular CiÄ¢¹½´«Ã½‘Ca therapy - as well as for complementary therapies, such as plasma exchange, adsorbers for cytokine removal* and low-flow extracorporeal CO2Ìýremoval on the multiFiltratePRO.

All products are concerted to complement each other and facilitate easy delivery of effective treatments on the ICU.

*in selected countries

CiÄ¢¹½´«Ã½‘Ca Dialysate

Ci-Ca Dialysate K2 + Ci-Ca Dialysate K4

With our range of CiÄ¢¹½´«Ã½‘Ca Dialysates,ÌýCiÄ¢¹½´«Ã½‘Ca therapyÌýcan be tailored to the patients' needs. CiÄ¢¹½´«Ã½‘Ca Dialysates are available in different potassium concentrations and with or without phosphate.

For more information on CKRT fluids available in your country, please contact your local Ä¢¹½´«Ã½ representative.

CKRT filters and plasma filters

Ultraflux AV 1000S

Ultraflux AV filters in CKRT

The Ultraflux AV filters10Ìýcontain a Fresenius Polysulfone membrane specially developed for CKRT. This membrane enables the elimination of smaller molecules such as uremic toxins and creatinine while plasma proteins like albumin, bigger molecules and cellular blood constituents are effectively retained.

Ä¢¹½´«Ã½'s CKRT filters offer a number of advantages:

  • Appropriate for CiÄ¢¹½´«Ã½‘Ca (RCA) and heparin anticoagulation
  • Steam sterilized
  • Up to 72 hours duration of use
  • A choice of different surface areas is available:ÌýUltraflux AV 600ÌýS (1.4 m2) and Ultraflux AV 1000ÌýS (1.8 m2)
Ultraflux EMiC 2

Ìý

Ultraflux EMiCÌý2 for the removal of middle molecules

In addition to the conventional goals of CKRT, such as the control of the fluid status and the correction of electrolyte abnormalities, an enhanced reduction of IL-6, IL-8, and myoglobin has been demonstrated using EMiC 211Ìýin comparison to Ultraflux AV 1000 S.1,2

The highÄ¢¹½´«Ã½‘permeability hemofilter Ultraflux EMiCÌý2 is used in CiÄ¢¹½´«Ã½‘Ca CVVHD treatments. It can improve the removal of middle molecules exceeding the molecular weight of commonly known small-sized uremic toxins such as urea and creatinine, while retaining albumin.1Ä¢¹½´«Ã½‘5

Ultraflux EMiCÌý2 at a glance:

  • Clearance of middle molecules such as myoglobin or interleukin-62
  • ClearanceÌýhas been demonstrated throughout citrate-anticoagulatedÌýCKRT for up to 72 hours3
  • Steep sieving coefficient curve3Ìýclosely mimics the physiological renal function
  • Substantially stable albumin levels1Ä¢¹½´«Ã½‘5
PlasmaFlux P1 dry

Ìý

plasmaFlux for therapeutic plasma exchange

Our plasma filter plasmaFlux is used for indications such as autoimmune diseases, metabolic diseases, endogenous and exogenous intoxications.6

plasmaFlux separates the plasma from the blood cells through the Polysulfone membrane. plasmaFlux is a non-prefilled plasma filter. The surface layer inside of the Plasmasulfone capillary is surrounded and stabilized by a second homogeneous, fine-pored layer.The Polysulfone membrane enables substances to pass, including plasma proteins such as immunoglobulins (e.g. IgM of 940 kDa) and lipoproteins (e.g. LDL of 2500 kDa).

Benefits:

  • Simplified setup due to dry delivery ofÌýplasmaFluxÌýP2 dry plasma filters - there is no need to stop priming to connect the plasma filter
  • Free passage of protein components even exceeding molecular weights of two million Dalton
  • Retaining blood cells

Low-flow CO2Ìýremoval with multiECCO2R

Low-flow CO2 removal with multiECCO2R

Ìý

CKRT treatments can be combined with various forms of organ support such as gas exchangers, with limited additional invasiveness.7ÌýLow-flow ECCO2R target blood flows can be achieved by efficient CKRT dialysis catheters, providing ease of use for CKRT system users.8

Ä¢¹½´«Ã½ offers with the multiECCO2R* a product for low-flow CO2Ìýremoval:

  • Applicable for both multiFiltratePRO and multiFiltrate
  • Gas exchanger placed downstream of the hemofilter, but upstream of air detector9
  • Blood flow max. 500 ml/min if anticoagulation with heparin planned9
  • Blood flow max. 200 ml/min if CiÄ¢¹½´«Ã½‘Ca anticoagulation used


* Legal manufacturer of multiECCO2RÌýis EUROSETS S.r.l., Italy. Ä¢¹½´«Ã½ Deutschland GmbH is a distributor of multiECCO2RÌýin selected countries.

Related content

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    1ÌýEichhorn T et al. Blood Purif 2017; 44(4);260Ä¢¹½´«Ã½‘266

    2ÌýWeidhase L et al. Crit Care 2020; 24(1):644

    3ÌýSiebeck M et al. Ther Apher Dial 2018; 22(4):355Ä¢¹½´«Ã½‘364

    4ÌýSchmidt JJ et al. Blood Purif 2012; 34:246Ä¢¹½´«Ã½‘252

    5ÌýWeidhase L et al. PLoS ONE 2019; 14:e0215823

    6ÌýInstruction for Use, plasmaFlux P1/P2 dry, valid from 05/2020

    7ÌýForster C et al. Crit Care 2013; 17:R154

    8ÌýStaudinger T. Perfusion 2020; 35:492-508

    9ÌýInstruction for use multiECCO2R, EU10306 - Rev. 04 2020/09/04

    10ÌýInstruction for use Ultraflux filters

    11ÌýInstruction for use EMiC2

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