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A Savior Overlooked

By Rice Powell, Chief Executive Officer and Chairman of the Management Board of Ģý

Ventilators arenĢýt the only medical equipment in short supply during the pandemic: Hospitals and clinics all over the world are in need of acute dialysis machines as well.

The world first got to know COVID-19 as a respiratory disease, and fears of ventilator shortages received global attention. As the worldĢýs leading provider of kidney care products and services, Ģý soon saw another rapidly growing demand: for acute dialysis machines. Ի now confirm what we realized early on Ģý around a third of the patients admitted to the hospital with COVID-19 develop acute kidney injury.

ĢýIf these folks are not dying of lung failure, theyĢýre dying of renal failure,Ģý neurologist Jennifer Frontera, who works for New York UniversityĢýs Langone Medical Center, told . The hospital has treated thousands of COVID-19 patients.

Kidneys are rich in ACE2 receptors, a target the virus uses to enter a cell. If the disease shuts down the patientsĢý organs, their natural function must be replaced. Kidney failure can be treated with renal replacement therapy, including forms of dialysis in which a machine cleans the patientsĢý blood and maintains their body fluids at a constant level. When COVID-19 led to an unprecedented surge in acute kidney injury, those dialysis machines, and the solutions, filters, and trained staff required to operate them were soon in short supply Ģý which could lead to the life-and-death calculations intensive care physicians are dreading.

We at Ģý were quick to realize our responsibility to help. Our teams in the U.S., Italy, China, and many other countries rushed to volunteer their knowledge and expertise to help local hospitals in the most heavily impacted regions.

Together, we made hundreds of acute dialysis devices and other supplies available when and where they were needed most Ģý in hospitals from China to Europe, North and Latin America and beyond. In Italy alone, our technical operations team installed as many acute dialysis machines in a month as it usually would in a year. In the U.S., we formed a National Intensive Renal Care Reserve to provide additional dialysis machines for the nationĢýs hospitals during this unprecedented crisis.

Together, we made hundreds of acute dialysis devices and other supplies available when and where they were needed most Ģý in hospitals from China to Europe, North and Latin America and beyond.

Rice Powell

Chief Executive Officer and Chairman of the Management Board

This growing need for our life-saving products came just when restrictions and lockdowns challenged our operations and supply chains. Despite increased safety measures, the teams showed extraordinary commitment. Our plants in the U.S. and Europe maximized their capacity and set themselves the ambitious goal of increasing the production of acute products by up to 200 percent. Meanwhile, colleagues in our supply chain also went out of their way to help Ģý you can imagine the complications one encounters when flying large shipments of medical goods straight into the hotspot of a pandemic.

I am inspired by the selflessness, commitment and determination that our employees worldwide are showing to keep our clinics, production sites and supply chains up and running. They truly put our patients first Ģý and now that the world needs their skills due to COVID-19, theyĢýre there as well. In this global fight against the pandemic, I am proud to be part of this industry-leading team.

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